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Secondary analyses adjusted for body mass index (BMI), alcohol intake, poverty income ratio (PIR), and education, as defined previously ( 2.5 Statistical analysis When analyzing ANA prevalence, we used logistic regression models to allow the probability of ANA positivity to depend on explanatory variables

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In our applications, which we submitted over two years ago, we believe that we appropriately characterized the toxicological profile of JUUL products, including comparisons to combustible cigarettes and other vapor products, and believe this data, along with the totality of the evidence, meets the statutory standard of being appropriate for the protection of the public health, he added